Hypoglycemic Activity of Gynura Procumbens in...

Background of the Study Diabetes mellitus is a serious metabolic disorder wherein the person has high blood glucose level either due to inadequate insulin production or the body’s cells do not respond properly to insulin (Nordqvist, 2010). There are three main types of diabetes namely Type I (insulin-dependent), Type II, and gestational diabetes. All these types are characterized by hyperglycemia or high blood glucose level. A person with diabetes may experience many symptoms such as high blood sugar, high glucose content in urine, weight loss, fatigue, nausea, vomiting, infections, blurred vision, and lethargy or coma (NDIC, 2013). Diabetes is continuing to be a major health problem in the world. The number of people with diabetes is†¦show more content†¦In the most recent study, the extract of G. procumbens was reported to produce significant elevation in the fasting blood glucose (FBG) levels of normal rats, but a decrease in diabetic rats (Hassan et al., 2010). Th us there is a need to further investigate the hypoglycemic activity of Gynura procumbens. Statement of the Problem What is the hypoglycemic activity of Gynura prcumbens leaf extract in alloxan-induced diabetic male mice? Objective of the Study The present study will be conducted to determine the hypoglycemic effect of Gynura procumbens (Lour.) Merr. in Alloxan-induced diabetic male mice. Significance of the Study Gynura procumbens grows extensively in Southeast Asia, where it is traditionally used for treatment of eruptive fevers, rash, kidney disease, migraines, constipation, hypertension, diabetes mellitus, and cancer (Rosidah, 2009). The investigation of Gynura procumbens will allow the researchers to assess its hypoglycemic activity. The results of this study can contribute to the knowledge about herbal plants with antidiabetic properties. The information from this study may aid in developing Gynura procumbens into a drug that will effectively lower the blood sugar levels in diabetic patients. Scope and Limitations of the Study This study focuses on the effectivity of Gynura procumbens plant extract as an alternative agent for lowering the bloodShow MoreRelatedComplications and Prevalence of Diabetes1391 Words   |  6 Pagesthese studies and information, it is therefore important to search for alternative diabetic medications such as herbal plants, which are natural, safe, effective, and inexpensive. Herbal Plants Many herbal plants have been investigated for their hypoglycemic. The active principles in these medicinal plants have been reported to possess pancreatic beta cells regenerating, insulin releasing, and fighting the problem of insulin resistance. These plants also have the ability to restore the function of